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Page 1
Crystal structure of strychnine hydrobromide.
ROBERTSON JH, BEEVERS CA. ROBERTSON JH, et al. Nature. 1950 Apr 29;165(4200):690-1. doi: 10.1038/165690a0. Nature. 1950. PMID: 15416785 No abstract available.
Application of high performance capillary electrophoresis on toxic alkaloids analysis.
Zhang L, Wang R, Zhang Y, Yu Y. Zhang L, et al. J Sep Sci. 2007 Jun;30(9):1357-63. doi: 10.1002/jssc.200600363. J Sep Sci. 2007. PMID: 17623479
We employed CE to identify mixtures of the toxic alkaloids lappaconitine, bullatine A, atropine sulfate, atropine methobromide, scopolamine hydrobromide, anisodamine hydrobromide, brucine, strychnine, quinine sulfate, and chloroquine in human blood and urine, …
We employed CE to identify mixtures of the toxic alkaloids lappaconitine, bullatine A, atropine sulfate, atropine methobromide, scopolamine …
Glycine transporter 1 (GlyT1) inhibitors exhibit anticonvulsant properties in the rat maximal electroshock threshold (MEST) test.
Kalinichev M, Starr KR, Teague S, Bradford AM, Porter RA, Herdon HJ. Kalinichev M, et al. Brain Res. 2010 May 17;1331:105-13. doi: 10.1016/j.brainres.2010.03.032. Epub 2010 Mar 18. Brain Res. 2010. PMID: 20303337
Thus, increasing extracellular concentration of glycine via inhibition of its uptake protects from electroshock-induced seizures in the rat. Whether strychnine-sensitive or strychnine-insensitive glycine binding sites are involved in this effect remains to be determ …
Thus, increasing extracellular concentration of glycine via inhibition of its uptake protects from electroshock-induced seizures in the rat. …
5-Hydroxytryptamine responses in neonate rat motoneurones in vitro.
Wang MY, Dun NJ. Wang MY, et al. J Physiol. 1990 Nov;430:87-103. doi: 10.1113/jphysiol.1990.sp018283. J Physiol. 1990. PMID: 2150862 Free PMC article.
Applied by superfusion (10-100 microM) or pressure ejection, 5-hydroxytryptamine (5-HT) elicited a slow depolarization (or inward current) in 81% and a hyperpolarization (or outward current) in 9% of responsive MNs; the responses persisted in a low-Ca2+, high-Mg2+ or tetrodotoxin …
Applied by superfusion (10-100 microM) or pressure ejection, 5-hydroxytryptamine (5-HT) elicited a slow depolarization (or inward current) i …
Atropine-resistant longitudinal muscle spasms due to excitation of non-cholinergic neurones in Auerbach's plexus.
Ambache N, Freeman MA. Ambache N, et al. J Physiol. 1968 Dec;199(3):705-27. doi: 10.1113/jphysiol.1968.sp008674. J Physiol. 1968. PMID: 5714581 Free PMC article.
The rapid twitch, lasting 3-8 sec, which is elicited by single shocks of 0.1 or 0.2 msec pulse width, and the effect of 5-15 ng doses of acetylcholine which matched this twitch, were both extinguished equally effectively and completely by atropine sulphate (0.4-1 x 10(-8) g/ml.) …
The rapid twitch, lasting 3-8 sec, which is elicited by single shocks of 0.1 or 0.2 msec pulse width, and the effect of 5-15 ng doses of ace …
Gycine and GABA interact to regulate the nitric oxide/cGMP signaling pathway in the turtle retina.
Yu D, Eldred WD. Yu D, et al. Vis Neurosci. 2005 Nov-Dec;22(6):825-38. doi: 10.1017/S0952523805226123. Vis Neurosci. 2005. PMID: 16469191 Free PMC article.
Our data show that blocking glycine receptors (GLYR) with strychnine (STRY) produced moderate increases in cGMP-like immunoreactivity (cGMP-LI) in select types of amacrine and bipolar cells, and strong increases in NO-induced fluorescence (NO-IF). ...CNQX, a selective anta …
Our data show that blocking glycine receptors (GLYR) with strychnine (STRY) produced moderate increases in cGMP-like immunoreactivity …
Simultaneous determination of six toxic alkaloids in human plasma and urine using capillary zone electrophoresis coupled to time-of-flight mass spectrometry.
Yu Z, Wu Z, Gong F, Wong R, Liang C, Zhang Y, Yu Y. Yu Z, et al. J Sep Sci. 2012 Oct;35(20):2773-80. doi: 10.1002/jssc.201200263. Epub 2012 Sep 20. J Sep Sci. 2012. PMID: 22997096
A novel capillary zone electrophoresis separation coupled to electro spray ionization time-of-flight mass spectrometry method was developed for the simultaneous analysis of six toxic alkaloids: brucine, strychnine, atropine sulfate, anisodamine hydrobromide, scopola …
A novel capillary zone electrophoresis separation coupled to electro spray ionization time-of-flight mass spectrometry method was developed …
Interaction of cholinergic and glutamatergic transmission in the hippocampus: an in vitro autoradiographic receptor analysis.
Deutsch SI, Panchision DM, Rosse RB, Novitzki MR, Miller LP, Mastropaolo J. Deutsch SI, et al. Neurosci Lett. 1990 Oct 2;118(1):124-7. doi: 10.1016/0304-3940(90)90264-a. Neurosci Lett. 1990. PMID: 1979670 Free article.
Quantitative in vitro receptor autoradiography was used to examine the effect of acute scopolamine administration on specific binding to components of the N-methyl-D-aspartate (NMDA) receptor complex in four regions of mouse hippocampus. The binding of [3H]glycine to the stryc …
Quantitative in vitro receptor autoradiography was used to examine the effect of acute scopolamine administration on specific binding to com …